Current methodologies for molecular screening of thyroid nodules
نویسندگان
چکیده
منابع مشابه
Current Diagnosis and Management of Thyroid Nodules.
Thyroid nodules are frequently found. Although they are often palpable, many are found incidentally during unrelated radiographic studies. Ten to 15% of thyroid nodules represents thyroid malignancy. Clinician suc as an internist/endocrinologist have to classify the nodule, stratify the risk of thyroid cancer, performed a diagnostic work-up, provide medical / non-surgical therapy, select candi...
متن کاملMolecular Diagnostics of Fine Needle Aspiration for the Presurgical Screening of Thyroid Nodules
"The incidence of thyroid cancer, the most common endocrine malignancy, is rising. The two most common types of thyroid cancer are papillary and follicular" thyroid carcinomas. "Fine-needle aspiration (FNA) of thyroid nodules" can permit to detect many genetic mutations and other molecular alterations, including RAS and BRAF point mutations, PAX8/peroxisome proliferator-activated receptor (PPAR...
متن کاملCurrent Radiological Approach in Thyroid Nodules
The aim of this paper is to review the radiological evaluation of thyroid nodules detected with ultrasonography (US), thoroughly and in harmony with the clinical-endocrinological-surgical management. In this review, we tried to summarize the radiological evaluation of nodules detected in the thyroid in compliance with recently published and accepted guidelines, including the most advanced sonog...
متن کاملLocal molecular analysis of indeterminate thyroid nodules
BACKGROUND Thyroid nodules are common but only a minority are malignant. Molecular testing can assist in helping determine whether indeterminate nodules are suspicious for malignancy or benign. The objective of the study was to determine if the analysis of mutations (BRAF, NRAS, KRAS and HRAS) using readily available molecular techniques can help better classify indeterminate thyroid nodules. ...
متن کاملDetermination of Ultrasonographic Characteristics of Thyroid Nodules for Thyroid Cancer Prediction
Background: In this study, we investigated the diagnostic power of ultrasound in the diagnosis of malignancy in thyroid nodules in Iranian patients. For this purpose, we examined the relationship between ultrasound findings and pathology findings. Methods: The present study is a retrospective study. The patients with a diagnosis of thyroid nodules who underwent ultrasound and FNA, were include...
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ژورنال
عنوان ژورنال: Gland Surgery
سال: 2018
ISSN: 2227-684X,2227-8575
DOI: 10.21037/gs.2017.08.04